Can You Donate Blood If You Smoke? Cannabis, Nicotine, and More Can Vaping Cause Lung Cancer? Here's What We Know. Can You Donate Plasma If You Smoke Weed? https: www.greenreliefhealth.com Smoking (or vaping) doesn't affect your ability to donate blood. Help us bust this myth by sharing our post. Can Smokers Donate Blood in India & its Side Effects? We all know smoking and vaping isn't great for your health. But it doesn't stop you from being a blood or plasma donor. Just make sure to wait one hour after donating